CJC-1295 + Ipamorelin + BPC-157 Calculator
Three peptides, three complementary mechanisms — GH axis optimization, tissue repair, and angiogenesis combined into one comprehensive research protocol.
Syringe Size
Which syringe will you use? (applies to all peptides below)
CJC-1295
GHRH receptor — GH pulse accelerator
Vial Size
BAC Water
Dose per Injection
Concentration
1.0 mg/mL
Volume
0.100 mL
Draw to
10.0 IU
Doses / vial
20
Ipamorelin
Ghrelin receptor — removes GH brake
Vial Size
BAC Water
Dose per Injection
Concentration
2.5 mg/mL
Volume
0.080 mL
Draw to
8.0 IU
Doses / vial
25
BPC-157
Tissue repair, angiogenesis, GH receptor upregulation
Vial Size
BAC Water
Dose per Injection
Concentration
2.5 mg/mL
Volume
0.100 mL
Draw to
10.0 IU
Doses / vial
20
Stack Overview
What You'll Need
Step-by-Step Guide
Follow these steps in order. Each step assumes you have no prior experience. Read each one fully before doing it.
This protocol uses three separate injections per day (or two per day with a simplified schedule). The key separation: BPC-157 goes in the MORNING (timing is flexible, food-independent). CJC-1295 and Ipamorelin go BEFORE SLEEP on an empty stomach (2+ hours after last meal). This separation is intentional — BPC-157 timing doesn't matter for GH axis effects, while the CJC+Ipa injection is timed to synchronize with nocturnal GH secretion. Never inject all three at the same time — you'd lose the timing benefit of the GH stack.
Wash your hands. On your first day, reconstitute all three vials at once to save time. Swab all three vial tops plus the bacteriostatic water vial. Let dry. Reconstitute one at a time: inject BAC water slowly down the glass wall, wait 60 seconds, gently swirl until dissolved. Label each vial with the date and peptide name. The three vials will look identical once reconstituted — labeling is critical.
Using a fresh insulin syringe, draw your BPC-157 dose (e.g. 250 mcg = 10 IU from a 2,500 mcg/mL solution). Inject subcutaneously in the abdomen. This morning injection is food-independent — you can eat before or after with no loss of effect. Dispose of the syringe in your sharps container.
Stop eating 2 hours before your planned injection time. A 9 PM injection means dinner should be finished by 7 PM at the latest. This window is non-negotiable for optimal GH response — insulin from food directly suppresses the GH release you're trying to trigger.
Using a fresh insulin syringe, draw your CJC-1295 dose first (e.g. 100 mcg = 10 IU from a 1,000 mcg/mL solution). Without changing the syringe, draw your Ipamorelin dose (e.g. 200 mcg = 8 IU from a 2,500 mcg/mL solution). The combined volume is small — typically 0.10–0.20 mL total. Inject subcutaneously, rotating to a different site than the morning injection. Go to sleep within 60 minutes.
With potentially two injections per day (morning BPC-157, evening CJC+Ipa), rotating injection sites is important to prevent subcutaneous tissue irritation. Divide your abdomen into quadrants: upper-left, upper-right, lower-left, lower-right. Move to a new quadrant each injection. Thighs can also be used for BPC-157. Give each site at least 3–4 days before returning to it.
All three reconstituted vials live in the refrigerator. Keep them upright (or on their side in a vial rack) away from the freezer section. Discard all three vials 28 days after reconstitution. If one vial's date comes before another, replace only that one — you don't need to reconstitute all three simultaneously again unless you want to.
Dosing Schedule
Simplified daily schedule:
Morning (any time, food timing flexible):
└ BPC-157: 250–500 mcg subcutaneously
Evening (30–60 min before sleep, 2+ hours after last meal):
└ CJC-1295: 100–200 mcg subcutaneously
└ Ipamorelin: 200–300 mcg subcutaneously (same syringe as CJC-1295)
Optional enhanced schedule (add fasted morning CJC+Ipa):
Fasted morning (before breakfast): CJC-1295 100 mcg + Ipamorelin 200 mcg
Mid-day: BPC-157 250 mcg
Pre-sleep: CJC-1295 100–200 mcg + Ipamorelin 200–300 mcg
**Cycle length:** 8–12 weeks on, 4 weeks off.
Why These Peptides Are Combined
This three-peptide combination targets body composition and recovery from two completely different biological directions simultaneously.
CJC-1295 + Ipamorelin optimize the growth hormone axis. As detailed in the dedicated CJC+Ipa blend guide, the two peptides activate complementary GH-releasing pathways in the pituitary (GHRH receptor and ghrelin receptor) for synergistic GH pulse amplitude. Sustained GH optimization supports: muscle protein synthesis, lipolysis (fat burning), collagen synthesis, bone mineral density, and cellular repair.
BPC-157 works at the tissue level through a completely separate mechanism — angiogenesis promotion (VEGFR2 pathway), direct fibroblast stimulation, and the nitric oxide system. These effects are particularly relevant for musculoskeletal repair, gut health, and localized tissue regeneration. BPC-157 has also been shown to upregulate growth hormone receptors locally, which may enhance the tissue-level response to the GH pulses generated by the CJC+Ipa component.
The synergy: GH provides the systemic anabolic signal; BPC-157 provides the vascular supply and local cellular machinery to act on that signal at the tissue level. The combination has become one of the most commonly discussed three-peptide research protocols precisely because the mechanisms genuinely complement rather than overlap.
