TB-500 (Thymosin Beta-4)
A synthetic version of the naturally occurring Thymosin Beta-4 protein, known for potent healing and anti-inflammatory effects.
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⚠ Research & Educational Use Only. TB-500 (Thymosin Beta-4) is a research chemical documented here for scientific education. All information references peer-reviewed literature and preclinical/clinical study data. Not for human consumption. Not medical advice. Consult a licensed researcher or healthcare professional before any laboratory use.
- Systemic healing — addresses injuries throughout the body
- Promotes tissue repair in tendons, ligaments, and muscles
- Reduces inflammation and oxidative stress
- TB-500 (Thymosin Beta-4) is not FDA-approved for human use. It is a research chemical for scientific study only.
Research At a Glance
- Systemic healing — addresses injuries throughout the body
- Promotes tissue repair in tendons, ligaments, and muscles
- Reduces inflammation and oxidative stress
- Enhances flexibility and range of motion
What is TB-500 (Thymosin Beta-4)?
Tap any underlined term for an instant definition.
TB-500 is a synthetic peptide derived from Thymosin Beta-4, a naturally occurring protein found in virtually all human and animal cells. It plays a crucial role in actin sequestration, cell migration, blood vessel development (angiogenesis), and wound healing. TB-500 is particularly noted for its systemic healing properties — unlike BPC-157 which works best locally, TB-500 circulates through the bloodstream and can address injuries throughout the body simultaneously. It is especially popular in veterinary research for treating injured horses and has been extensively studied for tendon, ligament, muscle, and cardiac repair.
Key Research Benefits
Documented effects observed in preclinical and clinical studies on TB-500 (Thymosin Beta-4). See all Healing & Recovery peptides for comparison.
Common Stacks
TB-500 (Thymosin Beta-4) is frequently combined with the following peptides for synergistic effects. Click any peptide to compare profiles before deciding.
The most popular healing stack - BPC-157 and TB-500 have complementary mechanisms covering local and systemic repair.
Adding a GH secretagogue amplifies the systemic anabolic and recovery signals TB-500 promotes.
Side Effects & Risks
Adverse effects reported in the research literature. All data sourced from preclinical and clinical study reports. View all peptides' side effects →
Dosing Data from the Literature
Doses referenced below are sourced from published preclinical and clinical studies. Use the peptide dose calculator to convert these values to injection volume.
Typical research dosing: 2–2.5 mg twice weekly for the first 4–6 weeks (loading phase), then 2–2.5 mg twice monthly for maintenance. TB-500 has a longer half-life than BPC-157, so less frequent dosing is needed.
Administration in Research Settings
Standard reconstitution and administration methodology for laboratory research use.
Reconstitute with bacteriostatic water. Can be administered subcutaneously or intramuscularly. Subcutaneous injection in the abdomen is most common. The loading phase helps saturate systemic levels. Often stacked with BPC-157 for comprehensive healing protocols.
Research Video
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Quick Reference
Research Articles
- FDA Peptide Reclassification 2026: What Researchers Need to Know10 min read
- Thymosin Alpha-1: The Immune-Optimizing Peptide Used Around the World8 min read
- TB-500: The Recovery Peptide Athletes Are Talking About8 min read
- BPC-157 for Pain: What the Research Actually Says9 min read
Research Use Only
This information is for educational research purposes only. This is not medical advice. Consult a qualified healthcare professional.