Curated by Dr. James T. Walker, PhD — Research DirectorProfiles sourced from peer-reviewed literature

Skin & Anti-Aging

Peptides that promote skin health, collagen production, and anti-aging effects

16 peptide profiles in this category. Browse the full directory to explore all 167 research peptides.

Skin & Anti-Aging2,450 views

Palmitoyl Tetrapeptide-7

A palmitoylated Gly-Gln-Pro-Arg peptide that suppresses inflammatory cytokines (IL-6, IL-8) and stimulates collagen production, reducing photoageing and chronic skin inflammation.

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Skin & Anti-Aging2,340 views

Melanotan II

A cyclic alpha-MSH analog with potent tanning, sexual function, and appetite-suppressing effects via broad melanocortin receptor activation.

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Skin & Anti-Aging0 views

Tetrapeptide-21

Tetrapeptide-21 (Lys-Asp-Val-Tyr) is a collagen-stimulating tetrapeptide that activates TGF-beta signaling in dermal fibroblasts to upregulate type I and III collagen synthesis. Compatible with Matrixyl and GHK-Cu.

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Skin & Anti-Aging1,120 views

Melanotan I

An alpha-MSH analog that stimulates melanin production for photoprotection, with a favourable side effect profile compared to Melanotan II.

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Skin & Anti-Aging3,210 views

Syn-Ake

A synthetic tripeptide that mimics the activity of Waglerin-1 from Temple Viper venom, blocking nicotinic acetylcholine receptors to produce muscle-relaxing, anti-wrinkle effects.

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Skin & Anti-Aging0 views

Tripeptide-10 Citrulline (Decorinyl)

Tripeptide-10 Citrulline (Decorinyl, Asp-Lys-Cit) mimics the decorin-binding site on collagen fibrils, promoting organized collagen fiber assembly and potentially reducing scar formation. Used in anti-aging and post-procedure formulations.

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Skin & Anti-Aging2,120 views

Tripeptide-29

Glycyl-prolyl-hydroxyproline (Gly-Pro-Hyp) - the most abundant tripeptide repeat unit in collagen, studied for its direct role in collagen fibril stabilisation and as a collagen synthesis signal.

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Skin & Anti-Aging2,150 views

Snap-8

An eight-residue acetylated peptide that competes with SNAP-25 to modulate neuromuscular junction signalling and reduce expression lines - a peptide alternative to botulinum toxin.

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Skin & Anti-Aging1,980 views

Vialox

Pentapeptide-3V - a synthetic cobra venom-derived peptide that blocks postsynaptic nicotinic acetylcholine receptors, reducing facial muscle contraction for non-injection wrinkle reduction.

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Skin & Anti-Aging0 views

Hexapeptide-11

Hexapeptide-11 (Peptamide-6) is a yeast fermentate-derived hexapeptide that stimulates fibroblast production of collagen, fibronectin, and laminin, and upregulates desmosome proteins involved in skin barrier integrity.

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Skin & Anti-Aging0 views

Myristoyl Pentapeptide-17

Myristoyl Pentapeptide-17 is a fatty-acid-modified pentapeptide studied for eyelash and eyebrow growth promotion by stimulating keratinocyte production of keratin proteins. Found in cosmetic lash serums and brow enhancement formulations.

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Skin & Anti-Aging2,980 views

Palmitoyl Pentapeptide-4 (Matrixyl)

A lipopeptide that stimulates collagen and glycosaminoglycan synthesis in fibroblasts, clinically shown to reduce wrinkle depth by up to 68% over 6 months.

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Skin & Anti-Aging2,123 views

GHK-Cu (Copper Peptide)

A naturally occurring copper complex with powerful skin regeneration, anti-aging, and wound healing properties.

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Skin & Anti-Aging2,280 views

Syn-Coll

Palmitoyl Tripeptide-5 - a TGF-beta mimetic lipopeptide that activates collagen I and III synthesis in dermal fibroblasts by mimicking the TSP-1 sequence that triggers TGF-beta activity.

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Skin & Anti-Aging2,340 views

Nonapeptide-1

A melanocortin-1 receptor antagonist peptide that blocks alpha-MSH binding to inhibit melanin production - used in skin brightening, hyperpigmentation, and melanogenesis research.

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Skin & Anti-Aging4,890 views

Argireline

Acetyl Hexapeptide-3/8 - a SNAP-25 mimetic that reduces muscle contraction at neuromuscular junctions, smoothing expression lines without needles.

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