Epitalon (Epithalon)
A tetrapeptide known as the 'fountain of youth peptide' for its telomere-lengthening and anti-aging properties.
Community Rating
No ratings yet
⚠ Research & Educational Use Only. Epitalon (Epithalon) is a research chemical documented here for scientific education. All information references peer-reviewed literature and preclinical/clinical study data. Not for human consumption. Not medical advice. Consult a licensed researcher or healthcare professional before any laboratory use.
- Activates telomerase — extends telomere length (anti-aging at cellular level)
- Regulates melatonin production and circadian rhythm
- Improves sleep quality, particularly in older subjects
- Epitalon (Epithalon) is not FDA-approved for human use. It is a research chemical for scientific study only.
Research At a Glance
- Activates telomerase — extends telomere length (anti-aging at cellular level)
- Regulates melatonin production and circadian rhythm
- Improves sleep quality, particularly in older subjects
- Potent antioxidant effects
What is Epitalon (Epithalon)?
Tap any underlined term for an instant definition.
Epitalon (also spelled Epithalon) is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) developed by Russian gerontologist Vladimir Khavinson at the St. Petersburg Institute of Bioregulation and Gerontology. It is considered one of the most important anti-aging peptides in research. Epitalon's primary mechanism is the activation of telomerase, the enzyme responsible for lengthening telomeres — the protective caps on chromosomes that shorten with each cell division. Shorter telomeres are directly associated with cellular aging. By activating telomerase, Epitalon has been shown to extend telomere length, potentially slowing or reversing some aspects of cellular aging. It also regulates melatonin production by the pineal gland.
Key Research Benefits
Documented effects observed in preclinical and clinical studies on Epitalon (Epithalon). See all Immune System peptides for comparison.
Common Stacks
Epitalon (Epithalon) is frequently combined with the following peptides for synergistic effects. Click any peptide to compare profiles before deciding.
A longevity-focused cognitive stack - Epitalon supports cellular aging and Semax provides neuroprotection and BDNF upregulation.
Both address aging at a fundamental level - Epitalon via telomere maintenance and NAD+ via sirtuin activation and DNA repair.
Epitalon's pineal gland effects pair well with DSIP's deep-sleep induction for a circadian rhythm restoration protocol.
Side Effects & Risks
Adverse effects reported in the research literature. All data sourced from preclinical and clinical study reports. View all peptides' side effects →
Dosing Data from the Literature
Doses referenced below are sourced from published preclinical and clinical studies. Use the peptide dose calculator to convert these values to injection volume.
Typical research dosing: 5–10 mg daily for 10–20 days, repeated 1–2 times per year. This cyclic protocol mirrors what was used in human longevity studies. Intranasal administration (10–20 mg/day) is also used. Some researchers use 100–200 mcg per kg body weight.
Administration in Research Settings
Standard reconstitution and administration methodology for laboratory research use.
Reconstitute with bacteriostatic water. Administer subcutaneously in the morning or evening. Annual cycles of 10–20 days are the most researched protocol. Intranasal delivery is possible but less common. Some combine with other anti-aging peptides like GHK-Cu and Thymalin.
Research Video
Explore Further
Quick Reference
Research Use Only
This information is for educational research purposes only. This is not medical advice. Consult a qualified healthcare professional.