Peptide Blends

Mod GRF 1-29 & GHRP-6 Blend

A research blend pairing Mod GRF 1-29 (CJC-1295 no DAC) with GHRP-6 for synergistic GH release while preserving physiological pulse patterns.

C152H252N44O42S / C46H56N12O6Half-life: Mod GRF: ~30-60 min; GHRP-6: ~1.5 hours

⚠ Research & Educational Use Only. Mod GRF 1-29 & GHRP-6 Blend is a research chemical documented here for scientific education. All information references peer-reviewed literature and preclinical/clinical study data. Not for human consumption. Not medical advice. Consult a licensed researcher or healthcare professional before any laboratory use.

Medically reviewed by Dr. Amanda Reid, MDWritten by the KnowYourPeptide Research TeamLast updated April 2026
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Key Takeaways
  • Synergistic GH pulses preserving physiological pulsatility
  • Mod GRF 1-29 DPP-IV resistance for improved duration vs native GHRH
  • GHRP-6 appetite stimulation alongside GH release
  • Mod GRF 1-29 & GHRP-6 Blend is not FDA-approved for human use. It is a research chemical for scientific study only.

Research At a Glance

  • Synergistic GH pulses preserving physiological pulsatility
  • Mod GRF 1-29 DPP-IV resistance for improved duration vs native GHRH
  • GHRP-6 appetite stimulation alongside GH release
  • Well-studied combination in research protocols

What is Mod GRF 1-29 & GHRP-6 Blend?

The Mod GRF 1-29 & GHRP-6 Blend pairs Modified GRF 1-29 (CJC-1295 without DAC) with GHRP-6. Unlike CJC-1295 with DAC, Mod GRF 1-29 has a half-life of 30-60 minutes, producing physiological GH pulses rather than continuous GH elevation. This is the most commonly referenced protocol in peer-reviewed research combining GHRH analogues and GHSPs.

What It Is

  • Mod GRF 1-29: GHRH 1-29 with four amino acid substitutions for DPP-IV resistance; half-life ~30-60 min
  • GHRP-6: GHS-R1a + motilin receptor agonist; strong appetite-stimulating GHS
  • Preferred by researchers who want synergistic GH release in physiological pulses (vs sustained elevation with DAC)
  • Historically one of the most-cited research GHRH + GHRP combinations

How It Works

  • Mod GRF 1-29 activates GHRHR with improved stability vs native GHRH
  • GHRP-6 simultaneously activates GHS-R1a and suppresses somatostatin
  • Combined GH pulses: 3-4x either peptide alone; pulse decays naturally within 3 hours
  • GHRP-6 appetite effect can be used to time nutrient delivery post-GH pulse

Key Research Findings

  • This exact combination is referenced in the majority of community research protocols
  • GH amplitude comparable to other GHRH + GHRP combinations (40-60 ng/mL peak in responsive subjects)
  • Twice-daily dosing maintains physiological pulsatility without receptor downregulation

Dosing From the Literature

  • Mod GRF 1-29 100-200 mcg + GHRP-6 100-200 mcg per injection
  • 2-3 times daily, with at least 3 hours between doses

Storage and Handling

  • Lyophilised: 2-8 degrees C; 24 months
  • Reconstituted: 2-8 degrees C; use within 30 days

Key Research Benefits

Documented effects observed in preclinical and clinical studies on Mod GRF 1-29 & GHRP-6 Blend. See all Peptide Blends peptides for comparison.

Synergistic GH pulses preserving physiological pulsatility
Mod GRF 1-29 DPP-IV resistance for improved duration vs native GHRH
GHRP-6 appetite stimulation alongside GH release
Well-studied combination in research protocols

Side Effects & Risks

Adverse effects reported in the research literature. All data sourced from preclinical and clinical study reports.

Appetite stimulation from GHRP-6
Transient cortisol elevation
Water retention at high doses

Dosing Data from the Literature

Doses referenced below are sourced from published preclinical and clinical studies. Use the peptide dose calculator to convert these values to injection volume.

Research Dosing Protocol

Mod GRF 1-29 100-200 mcg + GHRP-6 100-200 mcg per injection. 2-3 times daily (research protocols).

Enter your vial size and target dose to get the exact injection volume.

Administration in Research Settings

Standard reconstitution and administration methodology for laboratory research use.

Subcutaneous injection on empty stomach. GHRP-6 appetite effect makes pre-meal timing useful.

Explore Further

Quick Reference

Half-Life
Mod GRF: ~30-60 min; GHRP-6: ~1.5 hours
Formula
C152H252N44O42S / C46H56N12O6
Legal Status
Research chemicals. Not approved for human use.
Storage
Lyophilised: 2-8 degrees C. Reconstituted: 2-8 degrees C; use within 30 days.

Research Use Only

This information is for educational research purposes only. This is not medical advice. Consult a qualified healthcare professional.

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