Peptide Blends

Fragment 176-191 & CJC-1295 & Ipamorelin Blend

A research blend combining Fragment 176-191 (selective lipolytic hGH fragment) with CJC-1295 and ipamorelin for combined fat loss and GH-stimulating research.

Multiple componentsHalf-life: Fragment 176-191: ~1 hour; CJC-1295: ~30-60 min; Ipamorelin: ~2 hours

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⚠ Research & Educational Use Only. Fragment 176-191 & CJC-1295 & Ipamorelin Blend is a research chemical documented here for scientific education. All information references peer-reviewed literature and preclinical/clinical study data. Not for human consumption. Not medical advice. Consult a licensed researcher or healthcare professional before any laboratory use.

Medically reviewed by Dr. Amanda Haslett, MBChB MRCGPWritten by the KnowYourPeptide Research TeamLast updated April 2026
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Key Takeaways
  • Selective lipolysis from Fragment 176-191 without IGF-1 elevation
  • Synergistic GH release from CJC-1295 + ipamorelin
  • Combined fat loss + anabolic GH axis stimulation
  • Fragment 176-191 & CJC-1295 & Ipamorelin Blend is not FDA-approved for human use. It is a research chemical for scientific study only.

Research At a Glance

  • Selective lipolysis from Fragment 176-191 without IGF-1 elevation
  • Synergistic GH release from CJC-1295 + ipamorelin
  • Combined fat loss + anabolic GH axis stimulation
  • Fragment 176-191 preserves insulin sensitivity while CJC/ipamorelin elevates IGF-1

What is Fragment 176-191 & CJC-1295 & Ipamorelin Blend?

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The Fragment 176-191 & CJC-1295 & Ipamorelin Blend is a three-component research preparation designed to combine selective fat loss (via Fragment 176-191) with synergistic GH stimulation (via CJC-1295 + ipamorelin). This combination is specifically designed for body recomposition research, targeting simultaneous fat reduction and lean mass preservation.

What It Is

  • Fragment 176-191: C-terminal hGH fragment with selective lipolytic activity, no GH receptor binding, no elevation
  • CJC-1295 (no DAC): analogue for GHRHR-mediated pulsatile GH release
  • Ipamorelin: selective GHS-R1a agonist for complementary GH stimulation
  • Designed for simultaneous fat loss (Fragment mechanism) + anabolic GH support (CJC-1295 + ipamorelin)

How It Works

  • Fragment 176-191 activates beta-adrenergic receptor-like site on adipocytes, stimulating lipolysis and inhibiting lipogenesis independently of GH receptor
  • CJC-1295 + ipamorelin provide synergistic GH pulses (3-4x either alone), elevating for lean mass support
  • The combination produces fat loss without the insulin resistance of full hGH, while the GH component supports muscle preservation

Key Research Findings

  • Fragment 176-191 alone: 18-30% body fat reduction in obese rodent models over 4-6 weeks
  • CJC-1295 + ipamorelin component: 2-3 kg lean mass increase, 2% fat reduction at 6 months
  • No published head-to-head data on the triple combination vs each component

Dosing From the Literature

  • Fragment 176-191: 200-500 mcg subcutaneous, morning fasted
  • CJC-1295 (no DAC): 100-200 mcg per injection
  • Ipamorelin: 200-300 mcg per injection

Storage and Handling

  • Lyophilised: 2-8 degrees C; 24 months
  • : 2-8 degrees C; use within 21 days

Key Research Benefits

Documented effects observed in preclinical and clinical studies on Fragment 176-191 & CJC-1295 & Ipamorelin Blend. See all Peptide Blends peptides for comparison.

Selective lipolysis from Fragment 176-191 without IGF-1 elevation
Synergistic GH release from CJC-1295 + ipamorelin
Combined fat loss + anabolic GH axis stimulation
Fragment 176-191 preserves insulin sensitivity while CJC/ipamorelin elevates IGF-1

Side Effects & Risks

Adverse effects reported in the research literature. All data sourced from preclinical and clinical study reports. View all peptides' side effects →

Dosing Data from the Literature

Doses referenced below are sourced from published preclinical and clinical studies. Use the peptide dose calculator to convert these values to injection volume.

Research Dosing Protocol

Fragment 176-191 200-500 mcg + CJC-1295 100-200 mcg + Ipamorelin 200-300 mcg per injection.

Enter your vial size and target dose to get the exact injection volume.

Administration in Research Settings

Standard reconstitution and administration methodology for laboratory research use.

. Best administered in the morning fasted for lipolytic effects.

Explore Further

Quick Reference

Half-Life
Fragment 176-191: ~1 hour; CJC-1295: ~30-60 min; Ipamorelin: ~2 hours
Formula
Multiple components
Legal Status
Research chemicals. Not approved for human use.
Storage
Lyophilised: 2-8 degrees C. Reconstituted: 2-8 degrees C; use within 21 days.

Research Use Only

This information is for educational research purposes only. This is not medical advice. Consult a qualified healthcare professional.

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