Peptide Blends

CJC-1295 & GHRP-6 Blend

A research blend combining CJC-1295 (Mod GRF 1-29) with GHRP-6 for synergistic GH release paired with GHRP-6's notable appetite-stimulating effect.

C152H252N44O42S / C46H56N12O6Half-life: CJC-1295: ~30-60 min; GHRP-6: ~1.5 hours

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Compound Profile

CJC-1295 & GHRP-6 Blend

Key Data

FormulaC152H252N44O42S / C46H56N12O6
Half-lifeCJC-1295: ~30-60 min; GHRP-6: ~1.5 hours
CategoryPeptide Blends

Research reference only

Research Focus

Synergistic GH release via dual-receptor mechanism
GHRP-6 appetite stimulation useful in caloric surplus research
Strong GH pulse amplitude

Preclinical data

⚠ Research & Educational Use Only. CJC-1295 & GHRP-6 Blend is a research chemical documented here for scientific education. All information references peer-reviewed literature and preclinical/clinical study data. Not for human consumption. Not medical advice. Consult a licensed researcher or healthcare professional before any laboratory use.

Chemistry review: Ashish KumarWritten by the KnowYourPeptide Research TeamLast updated July 2026
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Key Takeaways
  • Synergistic GH release via dual-receptor mechanism
  • GHRP-6 appetite stimulation useful in caloric surplus research
  • Strong GH pulse amplitude
  • CJC-1295 & GHRP-6 Blend is not FDA-approved for human use. It is a research chemical for scientific study only.

Research At a Glance

  • Synergistic GH release via dual-receptor mechanism
  • GHRP-6 appetite stimulation useful in caloric surplus research
  • Strong GH pulse amplitude
  • Widely used combination in GH research protocols
Who researches this:Researchers studying combined GH secretagogue + appetite-stimulation protocolsThose investigating the ghrelin receptor appetite effects alongside sustained GHRH stimulationPeople researching muscle-building contexts where both elevated GH and increased food intake are research targetsScientists studying GHRP-6's appetite mechanism in a long-acting GHRH context
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In Plain English

Simple summary

CJC-1295 + GHRP-6 combines long-acting sustained GHRH stimulation with GHRP-6's ghrelin-like appetite-stimulating profile. The sustained GH elevation from CJC-1295-DAC combined with GHRP-6's strong hunger drive creates a protocol profile that's specifically relevant for research targets involving both increased GH and increased caloric intake -- such as muscle-building or recovery research contexts where driving a positive caloric environment is part of the research design.

  • Synergistic GH release via dual-receptor mechanism
  • GHRP-6 appetite stimulation useful in caloric surplus research
  • Strong GH pulse amplitude

The full scientific detail, mechanisms, citations, and dosing data, follows below.

What is CJC-1295 & GHRP-6 Blend?

Tap any underlined term for an instant definition.

CJC-1295 & GHRP-6 Blend pairs CJC-1295 (no DAC / Mod GRF 1-29) with GHRP-6. This combination mirrors the Mod GRF 1-29 + GHRP-6 protocol and is particularly relevant for research examining the interaction between GH axis stimulation and appetite/caloric intake, given GHRP-6's strong motilin-receptor-mediated appetite effect.

What It Is

  • CJC-1295 (no DAC):
  • GHRP-6: GHS-R1a + motilin with pronounced appetite-stimulating properties
  • Research application: studying combined GH + appetite effects; also used in mass-gaining body composition protocols

How It Works

  • GHRHR activation from CJC-1295 + GHS-R1a stimulation and somatostatin suppression from GHRP-6
  • Motilin receptor binding from GHRP-6 drives gastric motility and ghrelin-like appetite stimulation
  • GH pulses: 3-4x either peptide alone
  • Appetite stimulation onset: 20-40 minutes post-injection; duration 1-2 hours

Key Research Findings

  • GH response comparable to other + combinations
  • Appetite: Reliable caloric intake increase in research subjects; useful when caloric surplus is required
  • Lean mass: Strong gains when GHRP-6's appetite effect supports adequate caloric intake

Dosing From the Literature

  • CJC-1295 (no DAC) 100-200 mcg + GHRP-6 100-200 mcg per injection
  • Twice daily; administer before anticipated meals

Storage and Handling

  • Lyophilised: 2-8 degrees C; 24 months
  • : 2-8 degrees C; use within 30 days

By the Numbers

Sustained GH + hunger drive
CJC-1295-DAC provides sustained elevated GH; GHRP-6 adds regular hunger-stimulating ghrelin-like signaling
GHRP-6 ghrelin mimicry
GHRP-6 is the most ghrelin-like GHRP -- appetite effects are consistent and significant with each injection
Anabolic context use
The GH + appetite combination is relevant for research contexts targeting positive energy balance alongside GH axis stimulation

Key Research Benefits

Documented effects observed in preclinical and clinical studies on CJC-1295 & GHRP-6 Blend. See all Peptide Blends peptides for comparison.

Synergistic GH release via dual-receptor mechanism
GHRP-6 appetite stimulation useful in caloric surplus research
Strong GH pulse amplitude
Widely used combination in GH research protocols

Side Effects & Risks

Adverse effects reported in the research literature. All data sourced from preclinical and clinical study reports. View all peptides' side effects →

Dosing Data from the Literature

Doses referenced below are sourced from published preclinical and clinical studies. Use the peptide dose calculator to convert these values to injection volume.

Research Dosing Protocol

CJC-1295 (no DAC) 100-200 mcg + GHRP-6 100-200 mcg per injection. Twice daily.

Enter your vial size and target dose to get the exact injection volume.

Administration in Research Settings

Standard reconstitution and administration methodology for laboratory research use.

. Time GHRP-6 injection before meals if appetite stimulation is desired endpoint.

What the research doesn't show

The hunger effect of GHRP-6 is not subtle -- it's a consistent, notable increase in appetite that occurs within minutes of dosing. In research contexts where caloric intake is a controlled variable, GHRP-6's appetite effect is a significant confound. In practice, many protocols that list GHRP-6 are used specifically for this appetite-stimulating property alongside GH.

Medical Expert Videos

Physicians, researchers, and pharmacologists explain CJC-1295 & GHRP-6 Blend, covering mechanisms of action, clinical context, and study findings.

YouTube, CJC-1295 & GHRP-6 Blend · doctors & researchersOpen in YouTube

Videos sourced from YouTube search. KnowYourPeptide does not endorse any individual creator. For research education only.

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The Bottom Line

CJC-1295 & GHRP-6 Blend has a growing body of preclinical evidence and a well-characterised safety profile in research settings. The most-studied application is: synergistic gh release via dual-receptor mechanism.

The most commonly reported side effect in research subjects is pronounced appetite stimulation. It is a research chemical, not approved for human use.

Research chemicalNot for human useEducational purposes only

Frequently Asked Questions

Explore Further

Quick Reference

Half-Life
CJC-1295: ~30-60 min; GHRP-6: ~1.5 hours
Formula
C152H252N44O42S / C46H56N12O6
Legal Status
Research chemicals. Not approved for human use.
Storage
Lyophilised: 2-8 degrees C. Reconstituted: 2-8 degrees C; use within 30 days.

How It Compares

CJC-1295 + Ipamorelin achieves the sustained GH profile without the appetite drive. CJC-1295 + GHRP-2 offers similar potency with less appetite stimulation but more cortisol. GHRP-6 is uniquely appetite-stimulating -- if the research goal doesn't require hunger stimulation, ipamorelin is the preferred GHRP partner.

Compare CJC-1295 & GHRP-6 Blend side-by-side

Research Use Only

This information is for educational research purposes only. This is not medical advice. Consult a qualified healthcare professional.

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