CJC-1295 & GHRP-2 Blend
A potent research blend pairing CJC-1295 (Mod GRF 1-29) with GHRP-2 for strong synergistic GH release with good GH-axis selectivity.
Community Rating
No ratings yet
Compound Profile
CJC-1295 & GHRP-2 Blend
Key Data
Research reference only
Research Focus
Preclinical data
⚠ Research & Educational Use Only. CJC-1295 & GHRP-2 Blend is a research chemical documented here for scientific education. All information references peer-reviewed literature and preclinical/clinical study data. Not for human consumption. Not medical advice. Consult a licensed researcher or healthcare professional before any laboratory use.
- Strong GH pulse amplitude (3-5x each peptide alone)
- Good GH selectivity (less cortisol elevation than GHRP-6)
- Potent IGF-1 elevation for body composition research
- CJC-1295 & GHRP-2 Blend is not FDA-approved for human use. It is a research chemical for scientific study only.
Research At a Glance
- Strong GH pulse amplitude (3-5x each peptide alone)
- Good GH selectivity (less cortisol elevation than GHRP-6)
- Potent IGF-1 elevation for body composition research
- Well-characterized in human pharmacokinetic studies
In Plain English
Simple summaryCJC-1295 + GHRP-2 is the high-potency long-acting GH secretagogue combination -- pairing CJC-1295's 1-2 week GHRH half-life with GHRP-2's maximum GH release potency among GHRPs. The combination produces sustained high-level GHRH stimulation amplified by GHRP-2's potent ghrelin receptor activation. It's favored in research protocols targeting maximum GH output over extended periods, though GHRP-2's cortisol and prolactin effects accumulate with regular dosing in a way that ipamorelin-containing alternatives don't.
- Strong GH pulse amplitude
- Good GH selectivity
- Potent IGF-1 elevation for body composition research
The full scientific detail, mechanisms, citations, and dosing data, follows below.
What is CJC-1295 & GHRP-2 Blend?
Tap any underlined term for an instant definition.
CJC-1295 & GHRP-2 Blend combines CJC-1295 (no DAC / Mod GRF 1-29) with GHRP-2, a potent GHS-R1a agonist with excellent GH-stimulating efficacy. GHRP-2 produces stronger GH pulses than ipamorelin at equivalent doses but with modestly higher cortisol and prolactin elevation.
What It Is
- CJC-1295 (no DAC): GHRH analogue for GHRHR stimulation
- GHRP-2: potent GHS-R1a agonist; high GH output with moderate cortisol/prolactin side effect profile
- Selected when maximum GH amplitude is the research goal and clean selectivity (ipamorelin) is secondary
How It Works
- Standard GHRH + GHRP dual-receptor mechanism
- GHRP-2's higher GHS-R1a binding affinity vs ipamorelin produces somewhat larger GH peaks
- Combined GH amplitude: 3-5x either peptide alone
Key Research Findings
- GH peaks of 40-60 ng/mL in responsive individuals at standard doses
- IGF-1 elevation: 60-80% above baseline at 3 months
- Cortisol: transient 20-25% elevation above baseline at peak GHRP-2 concentration; normalizes within 3 hours
Dosing From the Literature
- CJC-1295 (no DAC) 100-200 mcg + GHRP-2 100-200 mcg per injection
- Twice daily; keep GHRP-2 below 250 mcg per injection
Storage and Handling
- Lyophilised: 2-8 degrees C; 24 months
- Reconstituted: 2-8 degrees C; use within 30 days
By the Numbers
Key Research Benefits
Documented effects observed in preclinical and clinical studies on CJC-1295 & GHRP-2 Blend. See all Peptide Blends peptides for comparison.
Side Effects & Risks
Adverse effects reported in the research literature. All data sourced from preclinical and clinical study reports. View all peptides' side effects →
Dosing Data from the Literature
Doses referenced below are sourced from published preclinical and clinical studies. Use the peptide dose calculator to convert these values to injection volume.
Administration in Research Settings
Standard reconstitution and administration methodology for laboratory research use.
Subcutaneous injection on empty stomach.
What the research doesn't show
GHRP-2's cortisol elevation is real and dose-dependent. In protocols where the research question involves understanding HPA axis responses alongside GH secretion, this is informative. In protocols where cortisol elevation is an unwanted confound, ipamorelin is the cleaner choice. The combination does produce the highest sustained GH levels of common pairings.
Medical Expert Videos
Physicians, researchers, and pharmacologists explain CJC-1295 & GHRP-2 Blend, covering mechanisms of action, clinical context, and study findings.
Videos sourced from YouTube search. KnowYourPeptide does not endorse any individual creator. For research education only.
The Bottom Line
CJC-1295 & GHRP-2 Blend has a growing body of preclinical evidence and a well-characterised safety profile in research settings. The most-studied application is: strong gh pulse amplitude.
The most commonly reported side effect in research subjects is moderate cortisol/prolactin elevation from ghrp-2. It is a research chemical, not approved for human use.
Frequently Asked Questions
Explore Further
Quick Reference
More in Peptide Blends
- Sermorelin & Ipamorelin Blend
- Sermorelin & GHRP-2 Blend
- Sermorelin & GHRP-6 Blend
- Sermorelin & GHRP-6 & GHRP-2 Triple Blend
How It Compares
CJC-1295 + Ipamorelin is the same long-acting GHRH with a cleaner, more selective GHRP. The choice between GHRP-2 and ipamorelin for CJC-1295 depends on whether maximum GH amplitude or endocrine selectivity is prioritized. For most research applications, ipamorelin's selective profile makes it the preferred GHRP partner.
Compare CJC-1295 & GHRP-2 Blend side-by-sideResearch Use Only
This information is for educational research purposes only. This is not medical advice. Consult a qualified healthcare professional.